Name

KNG1 Gene

kininogen 1

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]

kng1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term kng1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

KNG1 Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the KNG1 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

KNG1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for KNG1 from the Pathway Commons Protein-Protein Interactions dataset.

kng1adipoq Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term kng1adipoq in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.