Name

LIF Gene

leukemia inhibitory factor

The protein encoded by this gene is a pleiotropic cytokine with roles in several different systems. It is involved in the induction of hematopoietic differentiation in normal and myeloid leukemia cells, induction of neuronal cell differentiation, regulator of mesenchymal to epithelial conversion during kidney development, and may also have a role in immune tolerance at the maternal-fetal interface. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]

LIFR-AS1 Gene

LIFR antisense RNA 1

LIFR Gene

leukemia inhibitory factor receptor alpha

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

lif Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lif in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LIF Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LIF from the Pathway Commons Protein-Protein Interactions dataset.

gamma-aminobutyric acid receptor life cycle pathway Gene Set

From Biocarta Pathways

proteins participating in the gamma-aminobutyric acid receptor life cycle pathway pathway from the Biocarta Pathways dataset.

CNTF-CNTFR-gp130-LIFR complex Gene Set

From CORUM Protein Complexes

proteins in the CNTF-CNTFR-gp130-LIFR complex protein complex from the CORUM Protein Complexes dataset.

LIFR-LIF-gp130 complex Gene Set

From CORUM Protein Complexes

proteins in the LIFR-LIF-gp130 complex protein complex from the CORUM Protein Complexes dataset.

Life Expectancy Gene Set

From dbGAP Gene-Trait Associations

genes associated with the trait Life Expectancy in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

life expectancy Gene Set

From GAD Gene-Disease Associations

genes associated with the disease life expectancy in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

diet lifestyle and risk of colon cancer Gene Set

From GAD Gene-Disease Associations

genes associated with the disease diet lifestyle and risk of colon cancer in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

minimum lifetime body mass index Gene Set

From GAD Gene-Disease Associations

genes associated with the disease minimum lifetime body mass index in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

subjective quality of life Gene Set

From GAD Gene-Disease Associations

genes associated with the disease subjective quality of life in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

lifestylerelated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifestylerelated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

life Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term life in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifedeath Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifedeath in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifetimes Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifetimes in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifelong Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifelong in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifetime Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifetime in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifil11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifil11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifeguard Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifeguard in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifralphact3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifralphact3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifraumeni Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifraumeni in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifethreatening Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifethreatening in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifeexpectancy Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifeexpectancy in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifecycle Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifecycle in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifeevents Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifeevents in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifmediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifmediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifestyle Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifestyle in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifstat3mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifstat3mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifrbeta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifrbeta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifespan Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifespan in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

liflif Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term liflif in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

lifeacttransfected Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lifeacttransfected in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

determination of adult lifespan Gene Set

From GO Biological Process Annotations

genes participating in the determination of adult lifespan biological process from the curated GO Biological Process Annotations dataset.

viral life cycle Gene Set

From GO Biological Process Annotations

genes participating in the viral life cycle biological process from the curated GO Biological Process Annotations dataset.

Life threatening arrhythmia Gene Set

From GWAS Catalog SNP-Phenotype Associations

genes associated with the Life threatening arrhythmia phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations dataset.

anemia due to reduced life span of red cells Gene Set

From GWASdb SNP-Phenotype Associations

genes associated with the anemia due to reduced life span of red cells phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

anemia due to reduced life span of red cells Gene Set

From HPO Gene-Disease Associations

genes associated with the anemia due to reduced life span of red cells phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

Infantile Apparent Life-Threatening Event Gene Set

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Infantile Apparent Life-Threatening Event phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

extended life span Gene Set

From MPO Gene-Phenotype Associations

gene mutations causing the extended life span phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

LIFR Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LIFR from the Pathway Commons Protein-Protein Interactions dataset.

Late Phase of HIV Life Cycle Gene Set

From Reactome Pathways

proteins participating in the Late Phase of HIV Life Cycle pathway from the Reactome Pathways dataset.

Influenza Life Cycle Gene Set

From Reactome Pathways

proteins participating in the Influenza Life Cycle pathway from the Reactome Pathways dataset.

HIV Life Cycle Gene Set

From Reactome Pathways

proteins participating in the HIV Life Cycle pathway from the Reactome Pathways dataset.

Early Phase of HIV Life Cycle Gene Set

From Reactome Pathways

proteins participating in the Early Phase of HIV Life Cycle pathway from the Reactome Pathways dataset.