LLGL2 Gene

lethal giant larvae homolog 2 (Drosophila)

The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

LLGL2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LLGL2 from the Pathway Commons Protein-Protein Interactions dataset.

LLGL2-PAR-6B-PRKCI complex Gene Set

From CORUM Protein Complexes

proteins in the LLGL2-PAR-6B-PRKCI complex protein complex from the CORUM Protein Complexes dataset.