lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase)

The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

lrat Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term lrat in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LRAT Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LRAT from the Pathway Commons Protein-Protein Interactions dataset.

LRAT-like domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the LRAT-like domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.