Name

LTBP4 Gene

latent transforming growth factor beta binding protein 4

The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

ltbp4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ltbp4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LTBP4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LTBP4 from the Pathway Commons Protein-Protein Interactions dataset.