Name

MASP2 Gene

mannan-binding lectin serine peptidase 2

The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in two transcript variants encoding two RARF components that are involved in the mannan-binding lectin pathway of complement activation. The longer isoform is cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq, Jul 2008]

masp2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term masp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MASP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MASP2 from the Pathway Commons Protein-Protein Interactions dataset.

MASP2 deficiency Gene Set

From ClinVar Gene-Phenotype Associations

genes associated with the MASP2 deficiency phenotype from the curated ClinVar Gene-Phenotype Associations dataset.

MASP2 Deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease MASP2 Deficiency from the curated CTD Gene-Disease Associations dataset.

masp2ficolin3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term masp2ficolin3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

masp2 deficiency Gene Set

From OMIM Gene-Disease Associations

genes associated with the masp2 deficiency phenotype from the curated OMIM Gene-Disease Associations dataset.