Name

MBD1 Gene

methyl-CpG binding domain protein 1

The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]

mbd1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mbd1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MBD1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MBD1 from the Pathway Commons Protein-Protein Interactions dataset.

Replication-coupled CAF-1-MBD1-ETDB1 complex Gene Set

From CORUM Protein Complexes

proteins in the Replication-coupled CAF-1-MBD1-ETDB1 complex protein complex from the CORUM Protein Complexes dataset.

MBD1-MCAF complex Gene Set

From CORUM Protein Complexes

proteins in the MBD1-MCAF complex protein complex from the CORUM Protein Complexes dataset.

MBD1-Suv39h1-HP1 complex Gene Set

From CORUM Protein Complexes

proteins in the MBD1-Suv39h1-HP1 complex protein complex from the CORUM Protein Complexes dataset.

MBD1-MCAF1-SETDB1 complex Gene Set

From CORUM Protein Complexes

proteins in the MBD1-MCAF1-SETDB1 complex protein complex from the CORUM Protein Complexes dataset.

mbd1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mbd1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mbd1mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mbd1mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mbd1containing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mbd1containing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mbd1mcaf1setdb1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mbd1mcaf1setdb1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.