MCM3AP antisense RNA 1


minichromosome maintenance complex component 3 associated protein

The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. [provided by RefSeq, Jan 2014]

mcm3ap Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mcm3ap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MCM3AP Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MCM3AP from the Pathway Commons Protein-Protein Interactions dataset.