malignant fibrous histiocytoma amplified sequence 1

Identified in a human 8p amplicon, this gene is a potential oncogene whose expression is enhanced in some malignant fibrous histiocytomas (MFH). The primary structure of its product includes an ATP/GTP-binding site, three leucine zipper domains, and a leucine-rich tandem repeat, which are structural or functional elements for interactions among proteins related to the cell cycle, and which suggest that overexpression might be oncogenic with respect to MFH. [provided by RefSeq, Jul 2008]

MFHAS1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MFHAS1 from the Pathway Commons Protein-Protein Interactions dataset.