Name

MGAT5 Gene

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase

The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. [provided by RefSeq, Oct 2011]

MGAT5B Gene

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

The MGAT5B gene encodes a beta-1,6-N-acetylglucosaminyltransferase (EC 2.4.1.155) that functions in the synthesis of complex cell surface N-glycans (Kaneko et al., 2003 [PubMed 14623122]).[supplied by OMIM, Nov 2008]

mgat5 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mgat5 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mgat5modified Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mgat5modified in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mgat5mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mgat5mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MGAT5B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MGAT5B from the Pathway Commons Protein-Protein Interactions dataset.