Name

MLH1 Gene

mutL homolog 1

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]

mlh1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MLH1 Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for MLH1 from the MSigDB Cancer Gene Co-expression Modules dataset.

MLH1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MLH1 from the Pathway Commons Protein-Protein Interactions dataset.

MSH2-MSH6-PMS2-MLH1 complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MSH6-PMS2-MLH1 complex protein complex from the CORUM Protein Complexes dataset.

MSH2-MSH6-PMS1-MLH1 complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MSH6-PMS1-MLH1 complex protein complex from the CORUM Protein Complexes dataset.

EXO1-MLH1-PMS2 complex Gene Set

From CORUM Protein Complexes

proteins in the EXO1-MLH1-PMS2 complex protein complex from the CORUM Protein Complexes dataset.

PCNA-MLH1-PMS1 complex Gene Set

From CORUM Protein Complexes

proteins in the PCNA-MLH1-PMS1 complex protein complex from the CORUM Protein Complexes dataset.

MSH2-MLH1-PMS2 DNA-repair initiation complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2 DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

EXO1-MLH1-PCNA complex Gene Set

From CORUM Protein Complexes

proteins in the EXO1-MLH1-PCNA complex protein complex from the CORUM Protein Complexes dataset.

MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex Gene Set

From CORUM Protein Complexes

proteins in the MSH2-MLH1-PMS2-PCNA DNA-repair initiation complex protein complex from the CORUM Protein Complexes dataset.

hypermethylation of the mlh1 gene Gene Set

From GAD Gene-Disease Associations

genes associated with the disease hypermethylation of the mlh1 gene in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

mlh1positive Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1positive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1msh2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1msh2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1hypermethylated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1hypermethylated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1independent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1independent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1epm2aip1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1epm2aip1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1deficient Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1deficient in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1pms2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1pms2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

mlh1pms1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mlh1pms1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DNA mismatch repair protein Mlh1/HexB Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein Mlh1/HexB protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL322 (MLH1) Gene Set

From NURSA Protein Complexes

proteins in the BL322 (MLH1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

SC-582 (MLH1) Gene Set

From NURSA Protein Complexes

proteins in the SC-582 (MLH1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.