Name

NCR3 Gene

natural cytotoxicity triggering receptor 3

The protein encoded by this gene is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2010]

NCR3LG1 Gene

natural killer cell cytotoxicity receptor 3 ligand 1

B7H6 belongs to the B7 family (see MIM 605402) and is selectively expressed on tumor cells. Interaction of B7H6 with NKp30 (NCR3; MIM 611550) results in natural killer (NK) cell activation and cytotoxicity (Brandt et al., 2009 [PubMed 19528259]).[supplied by OMIM, Jan 2011]

ncr3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ncr3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NCR3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NCR3 from the Pathway Commons Protein-Protein Interactions dataset.

NCR3-CD247 complex Gene Set

From CORUM Protein Complexes

proteins in the NCR3-CD247 complex protein complex from the CORUM Protein Complexes dataset.

ncr3nkp30 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ncr3nkp30 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NCR3LG1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NCR3LG1 from the Pathway Commons Protein-Protein Interactions dataset.