negative elongation factor complex member B

NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]

nelfb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nelfb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NELFB Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NELFB from the Pathway Commons Protein-Protein Interactions dataset.