Name

NLRP6 Gene

NLR family, pyrin domain containing 6

The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

nlrp6 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nlrp6 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nlrp6avr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nlrp6avr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.