Name

NPTX2 Gene

neuronal pentraxin II

This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]

nptx2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nptx2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NPTX2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NPTX2 from the Pathway Commons Protein-Protein Interactions dataset.