Name

NR4A3 Gene

nuclear receptor subfamily 4, group A, member 3

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. The encoded protein may act as a transcriptional activator. The protein can efficiently bind the NGFI-B Response Element (NBRE). Three different versions of extraskeletal myxoid chondrosarcomas (EMCs) are the result of reciprocal translocations between this gene and other genes. The translocation breakpoints are associated with Nuclear Receptor Subfamily 4, Group A, Member 3 (on chromosome 9) and either Ewing Sarcome Breakpoint Region 1 (on chromosome 22), RNA Polymerase II, TATA Box-Binding Protein-Associated Factor, 68-KD (on chromosome 17), or Transcription factor 12 (on chromosome 15). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

nr4a3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nr4a3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NR4A3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NR4A3 from the Pathway Commons Protein-Protein Interactions dataset.

nr4a3ewsr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nr4a3ewsr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.