Name

NRF1 Gene

nuclear respiratory factor 1

This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1. [provided by RefSeq, May 2014]

NRF1 Gene Set

From ENCODE Transcription Factor Targets

target genes of the NRF1 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

nrf1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrf1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NRF1 Gene Set

From JASPAR Predicted Transcription Factor Targets

target genes of the NRF1 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

NRF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NRF1 from the Pathway Commons Protein-Protein Interactions dataset.

NRF1 Gene Set

From TRANSFAC Curated Transcription Factor Targets

target genes of the NRF1 transcription factor in low- or high-throughput transcription factor functional studies from the TRANSFAC Curated Transcription Factor Targets dataset.

NRF1 Gene Set

From TRANSFAC Predicted Transcription Factor Targets

target genes of the NRF1 transcription factor predicted using known transcription factor binding site motifs from the TRANSFAC Predicted Transcription Factor Targets dataset.

NRF1_GM12878_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_GM12878_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

NRF1_HepG2_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_HepG2_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

NRF1_H1-hESC_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_H1-hESC_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

NRF1_SK-N-SH_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_SK-N-SH_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

NRF1_K562_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_K562_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

NRF1_HeLa-S3_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the NRF1_HeLa-S3_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

nrf1binding Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrf1binding in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nrf1alphapal Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrf1alphapal in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nrf1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrf1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nrf1s Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term nrf1s in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 Gene Set

From GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations

genes differentially expressed following the nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.