NTRK3 Gene

neurotrophic tyrosine kinase, receptor, type 3

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

NTRK3-AS1 Gene

NTRK3 antisense RNA 1

ntrk3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ntrk3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

NTRK3 Gene Set

From KEA Substrates of Kinases

substrates of the kinase NTRK3 from the curated KEA Substrates of Kinases dataset.

NTRK3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for NTRK3 from the Pathway Commons Protein-Protein Interactions dataset.

NTRK3_drugactivation_67_GSE20358 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the NTRK3_drugactivation_67_GSE20358 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.