Name

OBSCN Gene

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

obscn Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term obscn in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

OBSCN Gene Set

From KEA Substrates of Kinases

substrates of the kinase OBSCN from the curated KEA Substrates of Kinases dataset.

OBSCN Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for OBSCN from the NURSA Protein-Protein Interactions dataset.

OBSCN Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for OBSCN from the Pathway Commons Protein-Protein Interactions dataset.