P2RY11 Gene

purinergic receptor P2Y, G-protein coupled, 11

The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is coupled to the stimulation of the phosphoinositide and adenylyl cyclase pathways and behaves as a selective purinoceptor. Naturally occuring read-through transcripts, resulting from intergenic splicing between this gene and an immediately upstream gene (PPAN, encoding peter pan homolog), have been found. The PPAN-P2RY11 read-through mRNA is ubiquitously expressed and encodes a fusion protein that shares identity with each individual gene product. [provided by RefSeq, Jul 2008]

PPAN-P2RY11 Gene

PPAN-P2RY11 readthrough

This locus represents naturally occurring read-through transcription between the adjacent PPAN and P2RY11 genes. Alternative splicing results in two transcript variants, one of which encodes a fusion protein that shares sequence identity with each individual gene product. This transcript is found to be ubiquitously expressed and is up-regulated by agents inducing granulocytic differentiation. However, its functional significance in vivo remains unclear. [provided by RefSeq, Nov 2010]

p2ry11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term p2ry11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

P2RY11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for P2RY11 from the Pathway Commons Protein-Protein Interactions dataset.