Name

PAPSS2 Gene

3'-phosphoadenosine 5'-phosphosulfate synthase 2

Sulfation is a common modification of endogenous (lipids, proteins, and carbohydrates) and exogenous (xenobiotics and drugs) compounds. In mammals, the sulfate source is 3'-phosphoadenosine 5'-phosphosulfate (PAPS), created from ATP and inorganic sulfate. Two different tissue isoforms encoded by different genes synthesize PAPS. This gene encodes one of the two PAPS synthetases. Defects in this gene cause the Pakistani type of spondyloepimetaphyseal dysplasia. Two alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

papss2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term papss2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PAPSS2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PAPSS2 from the Pathway Commons Protein-Protein Interactions dataset.

Defective PAPSS2 causes SEMD-PA Gene Set

From Reactome Pathways

proteins participating in the Defective PAPSS2 causes SEMD-PA pathway from the Reactome Pathways dataset.