Name

PARP1 Gene

poly (ADP-ribose) polymerase 1

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

PARP15 Gene

poly (ADP-ribose) polymerase family, member 15

PARP15 is a macrodomain-containing transcriptional repressor with poly(ADP-ribose) polymerase activity (Aguiar et al., 2005 [PubMed 16061477]).[supplied by OMIM, May 2008]

PARP16 Gene

poly (ADP-ribose) polymerase family, member 16

PARP14 Gene

poly (ADP-ribose) polymerase family, member 14

Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of enzymes that perform this modification (Ame et al., 2004 [PubMed 15273990]).[supplied by OMIM, Mar 2008]

PARP12 Gene

poly (ADP-ribose) polymerase family, member 12

PARP10 Gene

poly (ADP-ribose) polymerase family, member 10

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005 [PubMed 15674325]).[supplied by OMIM, Mar 2008]

PARP11 Gene

poly (ADP-ribose) polymerase family, member 11

PARP1P1 Gene

poly (ADP-ribose) polymerase family, member 1 pseudogene 1

PARP1P2 Gene

poly (ADP-ribose) polymerase family, member 1 pseudogene 2

parp1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PARP1 Gene Set

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein PARP1 from the curated Hub Proteins Protein-Protein Interactions dataset.

PARP1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP1 from the Pathway Commons Protein-Protein Interactions dataset.

CDK8-MED6-PARP1 complex Gene Set

From CORUM Protein Complexes

proteins in the CDK8-MED6-PARP1 complex protein complex from the CORUM Protein Complexes dataset.

WRN-Ku70-Ku80-PARP1 complex Gene Set

From CORUM Protein Complexes

proteins in the WRN-Ku70-Ku80-PARP1 complex protein complex from the CORUM Protein Complexes dataset.

NCOA6-DNA-PK-Ku-PARP1 complex Gene Set

From CORUM Protein Complexes

proteins in the NCOA6-DNA-PK-Ku-PARP1 complex protein complex from the CORUM Protein Complexes dataset.

parp1but Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1but in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1collaborates Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1collaborates in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1dnapkku80ku70topoisomerase Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1dnapkku80ku70topoisomerase in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1related Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1related in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1nuclear Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1nuclear in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1par Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1par in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1parg Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1parg in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1independent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1independent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp16 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp16 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp14 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp14 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp10 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp10 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

parp1nfkappabdna Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term parp1nfkappabdna in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL2492 (PARP10) Gene Set

From NURSA Protein Complexes

proteins in the BL2492 (PARP10) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

PARP12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP12 from the Pathway Commons Protein-Protein Interactions dataset.

PARP10 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP10 from the Pathway Commons Protein-Protein Interactions dataset.

PARP16 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP16 from the Pathway Commons Protein-Protein Interactions dataset.

PARP14 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP14 from the Pathway Commons Protein-Protein Interactions dataset.

PARP15 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP15 from the Pathway Commons Protein-Protein Interactions dataset.

PARP11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PARP11 from the Pathway Commons Protein-Protein Interactions dataset.