Name

PDK1 Gene

pyruvate dehydrogenase kinase, isozyme 1

Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]

PDK1P1 Gene

pyruvate dehydrogenase kinase, isozyme 1 pseudogene 1

pdk1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PDK1 Gene Set

From KEA Substrates of Kinases

substrates of the kinase PDK1 from the curated KEA Substrates of Kinases dataset.

PDK1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PDK1 from the Pathway Commons Protein-Protein Interactions dataset.

pdk1 Gene Set

From Phosphosite Textmining Biological Term Annotations

proteins co-occuring with the biological term pdk1 in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

PDK1 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase PDK1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

pdk1rapgef4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1rapgef4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1prk2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1prk2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1pkc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1pkc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1plk1myc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1plk1myc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1plcgamma1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1plcgamma1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1akt Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1akt in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1dependent Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1dependent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1src Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1src in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pdk1mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pdk1mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PDK1_knockout_80_GSE26290 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the PDK1_knockout_80_GSE26290 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

PDK1_knockout_265_GSE42187 Gene Set

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the PDK1_knockout_265_GSE42187 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.