Name

PFKM Gene

phosphofructokinase, muscle

Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]

PFKM Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for PFKM from the NURSA Protein-Protein Interactions dataset.

PFKM Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PFKM from the Pathway Commons Protein-Protein Interactions dataset.