Name |
---|
PHLPP1 GenePH domain and leucine rich repeat protein phosphatase 1 This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling. [provided by RefSeq, Dec 2011] |
PHLPP1 Gene SetFrom DEPOD Substrates of Phosphatases substrates of the phosphatase PHLPP1 from the curated DEPOD Substrates of Phosphatases dataset. |
phlpp1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term phlpp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PHLPP1 Gene SetFrom KEA Substrates of Kinases substrates of the kinase PHLPP1 from the curated KEA Substrates of Kinases dataset. |
PHLPP1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PHLPP1 from the Pathway Commons Protein-Protein Interactions dataset. |
BL2679 (PHLPP1) Gene Setproteins in the BL2679 (PHLPP1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |