Name

PHOX2B Gene

paired-like homeobox 2b

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. [provided by RefSeq, Jul 2008]

phox2b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term phox2b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PHOX2B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PHOX2B from the Pathway Commons Protein-Protein Interactions dataset.

phox2btlx2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term phox2btlx2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.