Name

PIAS2 Gene

protein inhibitor of activated STAT, 2

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]

PIAS2 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for PIAS2 from the NURSA Protein-Protein Interactions dataset.

PIAS2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PIAS2 from the Pathway Commons Protein-Protein Interactions dataset.

pias2beta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pias2beta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

E3 SUMO-protein ligase PIAS2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the E3 SUMO-protein ligase PIAS2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

BL2596 (PIAS2) Gene Set

From NURSA Protein Complexes

proteins in the BL2596 (PIAS2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2595 (PIAS2) Gene Set

From NURSA Protein Complexes

proteins in the BL2595 (PIAS2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL2594 (PIAS2) Gene Set

From NURSA Protein Complexes

proteins in the BL2594 (PIAS2) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.