PLCB1 Gene

phospholipase C, beta 1 (phosphoinositide-specific)

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

PLCB1-IT1 Gene

PLCB1 intronic transcript 1

PLCB1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PLCB1 from the Pathway Commons Protein-Protein Interactions dataset.

PLCB1-PARD3-PARD6A complex Gene Set

From CORUM Protein Complexes

proteins in the PLCB1-PARD3-PARD6A complex protein complex from the CORUM Protein Complexes dataset.

plcb1a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term plcb1a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.