POC1B Gene

POC1 centriolar protein B

POC1 proteins contain an N-terminal WD40 domain and a C-terminal coiled coil domain and are part of centrosomes. They play an important role in basal body and cilia formation. This gene encodes one of the two POC1 proteins found in humans. Mutation in this gene result in autosomal-recessive cone-rod dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]


POC1B-GALNT4 readthrough

This locus represents naturally occurring transcripts that splice the 5' exons of the POC1B (POC1 centriolar protein homolog B) gene on chromosome 12 to the GALNT4 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4) gene, which is located within a POC1B intron. Alternative splicing results in two transcript variants, one of which encodes a fusion isoform that shares sequence identity with the products of each individual gene. [provided by RefSeq, Dec 2010]

poc1b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term poc1b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

POC1B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for POC1B from the Pathway Commons Protein-Protein Interactions dataset.