POLG2 Gene

polymerase (DNA directed), gamma 2, accessory subunit

This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.[provided by RefSeq, Sep 2009]

polg2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term polg2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

POLG2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for POLG2 from the Pathway Commons Protein-Protein Interactions dataset.