Name

PRKAA1 Gene

protein kinase, AMP-activated, alpha 1 catalytic subunit

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

prkaa1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term prkaa1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PRKAA1 Gene Set

From KEA Substrates of Kinases

substrates of the kinase PRKAA1 from the curated KEA Substrates of Kinases dataset.

PRKAA1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PRKAA1 from the Pathway Commons Protein-Protein Interactions dataset.

PRKAA1 Gene Set

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase PRKAA1 from the curated PhosphoSitePlus Substrates of Kinases dataset.

prkaa12 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term prkaa12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL809 (PRKAA1) Gene Set

From NURSA Protein Complexes

proteins in the BL809 (PRKAA1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.