Name

PTGES Gene

prostaglandin E synthase

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]

PTGES2-AS1 Gene

PTGES2 antisense RNA 1 (head to head)

PTGES3 Gene

prostaglandin E synthase 3 (cytosolic)

PTGES2 Gene

prostaglandin E synthase 2

The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]

PTGES3L-AARSD1 Gene

PTGES3L-AARSD1 readthrough

This locus represents naturally occurring readthrough transcription between the neighboring PTGES3L (prostaglandin E synthase 3 (cytosolic)-like) and AARSD1(alanyl-tRNA synthetase domain containing 1) genes on chromosome 17. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, May 2012]

PTGES3L Gene

prostaglandin E synthase 3 (cytosolic)-like

PTGES3P3 Gene

prostaglandin E synthase 3 (cytosolic) pseudogene 3

PTGES3P1 Gene

prostaglandin E synthase 3 (cytosolic) pseudogene 1

PTGES Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTGES from the Pathway Commons Protein-Protein Interactions dataset.

ptges2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ptges2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PTGES3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTGES3 from the Pathway Commons Protein-Protein Interactions dataset.

PTGES2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTGES2 from the Pathway Commons Protein-Protein Interactions dataset.