Name

PTH Gene

parathyroid hormone

The protein encoded by this gene is a hormone secreted by parathyroid cells. This hormone elevates blood Ca2+ level by dissolving the salts in bone and preventing their renal excretion. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH). [provided by RefSeq, Jul 2008]

PTHLH Gene

parathyroid hormone-like hormone

The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013]

PTH2R Gene

parathyroid hormone 2 receptor

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

PTH2 Gene

parathyroid hormone 2

TIP39 is related to parathyroid hormone (PTH; MIM 168450) and PTH-related protein (PTHRP; MIM 168470) and is a ligand for PTH receptor-2 (PTHR2; MIM 601469) (John et al., 2002 [PubMed 11861531]).[supplied by OMIM, Mar 2008]

PTH1R Gene

parathyroid hormone 1 receptor

The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

pth Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pth in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PTH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTH from the Pathway Commons Protein-Protein Interactions dataset.

intermediate stratum of PThE Gene Set

From Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles

genes with high or low expression in intermediate stratum of PThE relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.

mantle zone of PThE Gene Set

From Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles

genes with high or low expression in mantle zone of PThE relative to other tissues from the Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles dataset.

G protein complex (PTHR1, GNB1, GNG2) Gene Set

From CORUM Protein Complexes

proteins in the G protein complex (PTHR1, GNB1, GNG2) protein complex from the CORUM Protein Complexes dataset.

pthirus pubis infestation Gene Set

From DISEASES Text-mining Gene-Disease Assocation Evidence Scores

genes co-occuring with the disease pthirus pubis infestation in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

ABX-PTH Gene Set

From DrugBank Drug Targets

interacting proteins for the ABX-PTH drug from the curated DrugBank Drug Targets dataset.

bone density; height; pth; pyridinoline, urinary Gene Set

From GAD Gene-Disease Associations

genes associated with the disease bone density; height; pth; pyridinoline, urinary in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

pthrppth1r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrppth1r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthresponsive Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthresponsive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pth1rtgfbr2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pth1rtgfbr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthrpinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrpinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthrp134mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrp134mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pth134 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pth134 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthreceptors Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthreceptors in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr394thr Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr394thr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthp1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthp1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pth2r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pth2r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthlh Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthlh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr9090hsp90alpha Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr9090hsp90alpha in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthrp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthr790met Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthr790met in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pth1r Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pth1r in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthpthrp Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthpthrp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthrelated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrelated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthrpexpressing Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthrpexpressing in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthdeficient Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthdeficient in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

pthinduced Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pthinduced in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PTHrP_KD_GDS1664_438_human_MDA-MB-231 Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the PTHrP_KD_GDS1664_438_human_MDA-MB-231 gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells Gene Set

From GEO Signatures of Differentially Expressed Genes for Gene Perturbations

genes differentially expressed following the PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells gene perturbation from the GEO Signatures of Differentially Expressed Genes for Gene Perturbations dataset.

[Tyr34]PTH-(3-34)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Tyr34]PTH-(3-34)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTHrP-(1-20)/TIP-(23-39) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the PTHrP-(1-20)/TIP-(23-39) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTH-(1-34) (rat) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the PTH-(1-34) (rat) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-21)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-21)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(3-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(3-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23 Tyr36]PTHrP-(1-36)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23 Tyr36]PTHrP-(1-36)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala1 12 Aib3 Gln10 hArg11 Trp14]PTH-(1-14)-NH2 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala1 12 Aib3 Gln10 hArg11 Trp14]PTH-(1-14)-NH2 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Arg19]PTH-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Arg19]PTH-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Tyr36]-PTHrP-(1-36) amide (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Tyr36]-PTHrP-(1-36) amide (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-28)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-28)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(5-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(5-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Glu19]PTHrP-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Glu19]PTHrP-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Nle8 18 Tyr34]PTH-(1-34)-NH2 (bovine) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Nle8 18 Tyr34]PTH-(1-34)-NH2 (bovine) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[D-Trp12 Tyr34]PTH-(7-34) (bovine) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [D-Trp12 Tyr34]PTH-(7-34) (bovine) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5]PTHrP-(1-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5]PTHrP-(1-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I][Nle8 21 Tyr34]PTH-(1-34)-NH2 (rat) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I][Nle8 21 Tyr34]PTH-(1-34)-NH2 (rat) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(2-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(2-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5]PTHrP-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5]PTHrP-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5]PTHrP-(1-36) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5]PTHrP-(1-36) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTHrP-(1-21)/PTH-(22-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the PTHrP-(1-21)/PTH-(22-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Tyr34]PTH-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Tyr34]PTH-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTHrP-(1-34) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the PTHrP-(1-34) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[D-Trp12]PTH-(7-34) (bovine) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [D-Trp12]PTH-(7-34) (bovine) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[His5]PTH-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [His5]PTH-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Trp23 Tyr36]PTHrP-(1-36)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Trp23 Tyr36]PTHrP-(1-36)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Trp23]PTHrP-(1-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Trp23]PTHrP-(1-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Val21]PTHrP-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Val21]PTHrP-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[His5 Arg19]PTH-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [His5 Arg19]PTH-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Glu19 Val21]PTHrP-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Glu19 Val21]PTHrP-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Phe23]PTH-(1-34) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Phe23]PTH-(1-34) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Nle8 18 Tyr34]PTH-(3-34)-NH2 (bovine) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Nle8 18 Tyr34]PTH-(3-34)-NH2 (bovine) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(1-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(1-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTHrP-(7-34) (human rat mouse) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the PTHrP-(7-34) (human rat mouse) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(4-36) (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(4-36) (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ile5 Trp23]PTHrP-(5-36) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ile5 Trp23]PTHrP-(5-36) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-34)-NH2 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Ala1 12 Aib3 Gln10 hArg11 Trp14 Arg19]PTH-(1-34)-NH2 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[Tyr34]PTH-(1-34)-NH2 (human) Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [Tyr34]PTH-(1-34)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

PTH2 Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the PTH2 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

PTHLH Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the PTHLH ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

low urinary cyclic amp response to pth administration Gene Set

From HPO Gene-Disease Associations

genes associated with the low urinary cyclic amp response to pth administration phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

elevated circulating parathyroid hormone (pth) level Gene Set

From HPO Gene-Disease Associations

genes associated with the elevated circulating parathyroid hormone (pth) level phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.

PTHB1, C-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PTHB1, C-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

PTHB1, N-terminal domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PTHB1, N-terminal domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Peptidyl-tRNA hydrolase, PTH2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Peptidyl-tRNA hydrolase, PTH2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

PTH2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTH2 from the Pathway Commons Protein-Protein Interactions dataset.

PTHLH Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTHLH from the Pathway Commons Protein-Protein Interactions dataset.

PTH2R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTH2R from the Pathway Commons Protein-Protein Interactions dataset.

PTH1R Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTH1R from the Pathway Commons Protein-Protein Interactions dataset.