PTPN14 Gene

protein tyrosine phosphatase, non-receptor type 14

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010]

PTPN14 Gene Set

From DEPOD Substrates of Phosphatases

substrates of the phosphatase PTPN14 from the curated DEPOD Substrates of Phosphatases dataset.

ptpn14 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ptpn14 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PTPN14 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PTPN14 from the Pathway Commons Protein-Protein Interactions dataset.