Name

PUF60 Gene

poly-U binding splicing factor 60KDa

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

puf60 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term puf60 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

PUF60 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PUF60 from the Pathway Commons Protein-Protein Interactions dataset.

puf60uhm Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term puf60uhm in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.