Name

RAP1A Gene

RAP1A, member of RAS oncogene family

This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. This protein is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. The encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

RAP1AP Gene

RAP1A, member of RAS oncogene family pseudogene

rap1a Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rap1a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RAP1A Gene Set

From MSigDB Cancer Gene Co-expression Modules

co-expressed genes for RAP1A from the MSigDB Cancer Gene Co-expression Modules dataset.

RAP1A Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RAP1A from the Pathway Commons Protein-Protein Interactions dataset.

ITGB1-RAP1A-PKD1 complex Gene Set

From CORUM Protein Complexes

proteins in the ITGB1-RAP1A-PKD1 complex protein complex from the CORUM Protein Complexes dataset.

Itgb1-Rap1a-Prkd1 complex Gene Set

From CORUM Protein Complexes

proteins in the Itgb1-Rap1a-Prkd1 complex protein complex from the CORUM Protein Complexes dataset.

rap1abeta1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rap1abeta1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.