Name

RAPGEF1 Gene

Rap guanine nucleotide exchange factor (GEF) 1

This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008]

rapgef1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rapgef1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RAPGEF1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RAPGEF1 from the Pathway Commons Protein-Protein Interactions dataset.

Cbl-Crkl-Rapgef1 complex Gene Set

From CORUM Protein Complexes

proteins in the Cbl-Crkl-Rapgef1 complex protein complex from the CORUM Protein Complexes dataset.

CRKL-PDGFRA-CRK-RAPGEF1 complex Gene Set

From CORUM Protein Complexes

proteins in the CRKL-PDGFRA-CRK-RAPGEF1 complex protein complex from the CORUM Protein Complexes dataset.

BL7865 (RAPGEF1) Gene Set

From NURSA Protein Complexes

proteins in the BL7865 (RAPGEF1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

BL7864 (RAPGEF1) Gene Set

From NURSA Protein Complexes

proteins in the BL7864 (RAPGEF1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.