Name

RASD1 Gene

RAS, dexamethasone-induced 1

This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]

rasd1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rasd1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RASD1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RASD1 from the Pathway Commons Protein-Protein Interactions dataset.