Name

RASGRP3 Gene

RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]

rasgrp3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rasgrp3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RASGRP3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RASGRP3 from the Pathway Commons Protein-Protein Interactions dataset.