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RBBP7 Generetinoblastoma binding protein 7 This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] |
rbbp7 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term rbbp7 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
RBBP7 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for RBBP7 from the Pathway Commons Protein-Protein Interactions dataset. |
BL2989 (RBBP7) Gene Setproteins in the BL2989 (RBBP7) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset. |