Name

RFXAP Gene

regulatory factor X-associated protein

Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene. [provided by RefSeq, Jul 2008]

rfxap Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rfxap in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RFXAP Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for RFXAP from the NURSA Protein-Protein Interactions dataset.

RFXAP Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RFXAP from the Pathway Commons Protein-Protein Interactions dataset.

rfxapc Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rfxapc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

BL327 (RFXAP) Gene Set

From NURSA Protein Complexes

proteins in the BL327 (RFXAP) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.