Harmonizome

ribosomal protein S6 kinase, 90kDa, polypeptide 3

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in this gene have been associated with Coffin-Lowry syndrome (CLS). [provided by RefSeq, Jul 2008]

From Hub Proteins Protein-Protein Interactions

interacting proteins for hub protein RPS6KA3 from the curated Hub Proteins Protein-Protein Interactions dataset.

From KEA Substrates of Kinases

substrates of the kinase RPS6KA3 from the curated KEA Substrates of Kinases dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for RPS6KA3 from the Pathway Commons Protein-Protein Interactions dataset.

From PhosphoSitePlus Substrates of Kinases

substrates of the kinase RPS6KA3 from the curated PhosphoSitePlus Substrates of Kinases dataset.

From GEO Signatures of Differentially Expressed Genes for Kinase Perturbations

genes differentially expressed following the RPS6KA3_knockout_73_GSE22137 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

From NURSA Protein Complexes

proteins in the EPI-1482-1 (RPS6KA3) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

From NURSA Protein Complexes

proteins in the EPI-1474-1 (RPS6KA3) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.