Name

RUNX3 Gene

runt-related transcription factor 3

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RUNX3 Gene Set

From ENCODE Transcription Factor Targets

target genes of the RUNX3 transcription factor in ChIP-seq datasets from the ENCODE Transcription Factor Targets dataset.

runx3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term runx3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

RUNX3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for RUNX3 from the Pathway Commons Protein-Protein Interactions dataset.

RUNX3_GM12878_hg19_2 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the RUNX3_GM12878_hg19_2 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

RUNX3_GM12878_hg19_1 Gene Set

From ENCODE Transcription Factor Binding Site Profiles

genes with transcription factor binding evidence in the RUNX3_GM12878_hg19_1 transcription factor binding site profile from the ENCODE Transcription Factor Binding Site Profiles dataset.

runx3mediated Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term runx3mediated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

runx3binding Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term runx3binding in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

runx3aml2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term runx3aml2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.