Name

S100B Gene

S100 calcium binding protein B

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]

s100b Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100b in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

S100B Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for S100B from the Pathway Commons Protein-Protein Interactions dataset.

s100beta Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100beta in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

s100bp53 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100bp53 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

s100bp90 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100bp90 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

s100betapositive Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100betapositive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

s100bb Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100bb in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

s100bfgf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term s100bfgf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.