SCP2 Gene

sterol carrier protein 2

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.[provided by RefSeq, Aug 2010]

SCP2D1 Gene

SCP2 sterol-binding domain containing 1

scp2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term scp2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SCP2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SCP2 from the Pathway Commons Protein-Protein Interactions dataset.

SCP2 sterol-binding domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the SCP2 sterol-binding domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.