SDC2 Gene

syndecan 2

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-2 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-2 expression has been detected in several different tumor types. [provided by RefSeq, Jul 2008]

sdc2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sdc2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SDC2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SDC2 from the Pathway Commons Protein-Protein Interactions dataset.

Sdc2-Ephb2 complex Gene Set

From CORUM Protein Complexes

proteins in the Sdc2-Ephb2 complex protein complex from the CORUM Protein Complexes dataset.