SEMG2 Gene

semenogelin II

The secreted protein encoded by this gene is involved in the formation of a gel matrix that encases ejaculated spermatozoa. Proteolysis by the prostate-specific antigen (PSA) breaks down the gel matrix and allows the spermatozoa to move more freely. The encoded protein is found in lesser abundance than a similar semenogelin protein. An antibacterial activity has been found for a antimicrobial peptide isolated from this protein. The genes encoding these two semenogelin proteins are found in a cluster on chromosome 20. [provided by RefSeq, Jan 2015]

semg2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term semg2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SEMG2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SEMG2 from the Pathway Commons Protein-Protein Interactions dataset.