Name

SERPINF2 Gene

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

serpinf2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term serpinf2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SERPINF2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SERPINF2 from the Pathway Commons Protein-Protein Interactions dataset.