Harmonizome

SH3-domain GRB2-like 1

This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

SH3-domain GRB2-like 1 pseudogene 2

SH3-domain GRB2-like 1 pseudogene 3

SH3-domain GRB2-like 1 pseudogene 1

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term sh3gl1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SH3GL1 from the Pathway Commons Protein-Protein Interactions dataset.