Name

SHMT1 Gene

serine hydroxymethyltransferase 1 (soluble)

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

SHMT1P1 Gene

serine hydroxymethyltransferase 1 (soluble) pseudogene 1

shmt1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term shmt1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

SHMT1 Gene Set

From NURSA Protein-Protein Interactions

interacting proteins for SHMT1 from the NURSA Protein-Protein Interactions dataset.

SHMT1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SHMT1 from the Pathway Commons Protein-Protein Interactions dataset.

shmt11420t Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term shmt11420t in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.